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Research information about CFS - Chronic Fatigue Syndrome

Friends International FMS-CFS website has joined a partnering with Phoenix Rising. The Phoenix Rising website has the most extensive summaries of CFS research found on the web.

The website is well known for the monthly newsletters that provide extensive information on latest CFS news and research. Among other things it contains analyses of current CFS research studies. These are not simply abstracts of CFS studies they are often extensive summaries that tie together new, old and upcoming research. The newsletter also often contains CFS stories.

Watch The ME - CFS video!


The following provide summaries of many of the current research topics in CFS. Unfortunately, links had to be removed due to the content no longer being present. The summaries remain for informational purposes.


The fatigue in CFS is it central? - this paper examines the increasing evidence that the brain plays a pivotal role in the fatigue found in CFS.

A neurological channelopathy in CFS? One group of researchers thinks an ion channel dysfunction in the central nervous system is responsible for CFS.

Does CFS patients have selfish brains? - These authors propose that an altered energy 'set point' in the brains of CFS patients may be at the heart of CFS.


Dr. Cheney's latest theory regarding CFS has put cardiovascular issues front and center for the first time for many CFS patients. This section of the website has seven papers including testing the heart in CFS. Read about potential causes and ongoing research to see what the heart studies have found in CFS.

Dr Cheney believes diastolic heart problems play a key role in CFS. Free radicals may play a critical role in heart disease and heart failure. These papers examine the effects superoxide, nitric oxide, peroxynitrite and antioxidants have on the heart.


Glutathione is the master anti-oxidant in the body. The papers by Rich Von Konynenburg examine the evidence for glutathione depletion in CFS and ways of enhancing it. Read how findings of low glutathione in autism may have implications for our understanding of CFS. Discover the many different ways used to boost the levels of this master antioxidant in the body. Everyone with CFS should give glutathione supplementation a try.


The following papers explore the evidence for hypocortisolism (low cortisol levels) in CFS and looks at it's possible causes and effects.


Take advantage of several recent studies to look at the different theories regarding how the pain in FMS is caused:

Fibromyalgia is a brain disorder

Fibromyalgia is a muscle disorder


Researchers are finding that in CFS, like other complex diseases, multiple gene mutations occurring in variety of immune, endocrine and neurological genes may predispose one to CFS. This is a hot field of research right now.


Is a model of post-infective fatigue emerging? - The Dubbo Studies are a fascinating set of studies that are examining people infected one of three pathogens (Ross-River VIrus), Epstein-Barr Virus, Coxiella Burnetii) that are known to trigger CFS.

If you have any questions or need help, join us at the message board in the forum called Coping and health problems. The support group is a very experienced, active and caring group of people.


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